A patent review of SHP2 allosteric inhibitors (2018-present)
Author:
Affiliation:
1. Principal Research Investigator, IRBM S.p.A. - Medicinal Chemistry, Rome, Italy
Funder
Collezione Nazionale dei Composti chimici e Centro Screening
Publisher
Informa UK Limited
Link
https://www.tandfonline.com/doi/pdf/10.1080/13543776.2024.2365410
Reference97 articles.
1. Molecular mechanism of SHP2 activation by PD-1 stimulation
2. Recent advances in the discovery of protein tyrosine phosphatase SHP2 inhibitors
3. Crystal Structure of the Tyrosine Phosphatase SHP-2
4. A comprehensive review of SHP2 and its role in cancer
5. Activating Mutation of SHP2 Establishes a Tumorigenic Phonotype Through Cell-Autonomous and Non-Cell-Autonomous Mechanisms
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