A patent review of glutaminyl cyclase inhibitors (2004–present)-Reference-Cited by-同舟云学术

A patent review of glutaminyl cyclase inhibitors (2004–present)

Published:2021-07-05 Issue:9 Volume:31 Page:809-836
ISSN:1354-3776
Container-title:Expert Opinion on Therapeutic Patents
language:en
Short-container-title:Expert Opinion on Therapeutic Patents

Author:

Coimbra Judite R.M.¹²^ORCID,Salvador Jorge A.R.¹²^ORCID

Affiliation:

1. Laboratory of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal

2. Center for Neuroscience and Cell Biology (CNC), Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Coimbra, Portugal

Funder

the European Regional Development Fund

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/13543776.2021.1917549

Reference128 articles.

1. Identification of a mammalian glutaminyl cyclase converting glutaminyl into pyroglutamyl peptides.

2. Primary structure and functional expression of a glutaminyl cyclase.

3. Mammalian glutaminyl cyclases and their isoenzymes have identical enzymatic characteristics

4. Isolation of an Isoenzyme of Human Glutaminyl Cyclase: Retention in the Golgi Complex Suggests Involvement in the Protein Maturation Machinery

5. Glutaminyl Cyclase Knock-out Mice Exhibit Slight Hypothyroidism but No Hypogonadism

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. BACE1 Inhibitors for Alzheimer’s Disease: Current Challenges and Future Perspectives;Journal of Alzheimer's Disease;2024-06-22

2. Isoglutaminyl Cyclase Overexpression Enhances KYSE30 Cancer Cell Proliferation and Migration via the MAPK Signaling Pathway;Journal of Proteome Research;2024-04-24

3. Discovery of potential scaffolds for glutaminyl cyclase inhibitors: Virtual screening, synthesis, and evaluation;Bioorganic & Medicinal Chemistry;2024-01

4. Therapeutic potential of glutaminyl cyclases: Current status and emerging trends;Drug Discovery Today;2023-10

5. Development and evolution of human glutaminyl cyclase inhibitors (QCIs): an alternative promising approach for disease-modifying treatment of Alzheimer's disease;Frontiers in Aging Neuroscience;2023-08-03