Biotransformation of a crizotinib intermediate using a mutant alcohol dehydrogenase of Lactobacillus kefir coupled with glucose dehydrogenase-Reference-Cited by-同舟云学术

Biotransformation of a crizotinib intermediate using a mutant alcohol dehydrogenase of Lactobacillus kefir coupled with glucose dehydrogenase

Published:2019-04-07 Issue:6 Volume:49 Page:578-583
ISSN:1082-6068
Container-title:Preparative Biochemistry and Biotechnology
language:en
Short-container-title:Preparative Biochemistry and Biotechnology

Author:

Zong Chuhong¹,Zhang Xu²,Yang Fei³,Zhou Yafeng¹,Chen Nan¹,Yang Zuisu¹,Ding Guofang¹,Yu Fangmiao¹^ORCID,Tang Yunping¹^ORCID

Affiliation:

1. Zhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan, China;

2. Microbiology Institute of Shaanxi Shaanxi Academy of Sciences, Xi'an, China;

3. Hangzhou Obstetrics and Gynecology Hospital, Hangzhou, China

Funder

National Natural Science Foundation of China

National Undergraduate Training Program for Innovation and Entrepreneurship

Zhejiang Xinmiao Talents Program

Publisher

Informa UK Limited

Subject

General Medicine,Biochemistry,Biotechnology

Link

https://www.tandfonline.com/doi/pdf/10.1080/10826068.2019.1591987

Reference26 articles.

1. Crizotinib for the Treatment of ALK-Rearranged Non-Small Cell Lung Cancer: A Success Story to Usher in the Second Decade of Molecular Targeted Therapy in Oncology

2. Ceritinib inALK-Rearranged Non–Small-Cell Lung Cancer

3. Clinical Experience With Crizotinib in Patients With Advanced ALK-Rearranged Non–Small-Cell Lung Cancer and Brain Metastases

4. Fit-for-Purpose Development of the Enabling Route to Crizotinib (PF-02341066)

5. A novel approach for the synthesis of Crizotinib through the key chiral alcohol intermediate by asymmetric hydrogenation using highly active Ir-Spiro-PAP catalyst

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