Fit-for-Purpose Development of the Enabling Route to Crizotinib (PF-02341066)

Author:

de Koning Pieter D.1,McAndrew Douglas1,Moore Robert1,Moses Ian B.1,Boyles David C.2,Kissick Kyle2,Stanchina Corey L.2,Cuthbertson Timothy3,Kamatani Asayuki3,Rahman Leera3,Rodriguez Rick3,Urbina Armando3,Sandoval (née Accacia) Alison4,Rose Peter R.4

Affiliation:

1. Pfizer Global Research and Development, Ramsgate Road, Sandwich, Kent CT13 9NJ, United Kingdom

2. Pfizer Global Research and Development, 2800 Plymouth Road, Ann Arbor, Michigan 48105, United States

3. Pfizer Global Research and Development, 10578 Science Center Drive, San Diego, California 92121, United States

4. Pfizer Global Research and Development, Eastern Point Road, Groton, Connecticut 06340, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Reference16 articles.

1. An Orally Available Small-Molecule Inhibitor of c-Met, PF-2341066, Exhibits Cytoreductive Antitumor Efficacy through Antiproliferative and Antiangiogenic Mechanisms

2. Pfizer pipeline as of Feb 28, 2011:http://www.pfizer.com/files/research/pipeline/2011_0228/pipeline_2011_0228.pdf.

3. Crizotinib — Latest Champion in the Cancer Wars?

4. Cui, J. J.; Botrous, I.; Shen, H.; Tran-Dube, M. B.; Nambu, M. D.; Kung, P.P.; Funk, L. A.; Jia, L.; Meng, J. J.; Pairish, M. A.; McTigue, M.; Grodsky, N.; Ryan, K.; Alton, G.; Yamazaki, S.; Zou, H.; Christensen, J. G.; Mroczkowski, B.Abstracts of Papers; 235th ACS National Meeting, New Orleans, LA, United States, April 6–10, 2008.

5. Cui, J. J.; Funk, L. A.; Jia, L.; Kung, P.P.; Meng, J. J.; Nambu, M. D.; Pairish, M. A.; Shen, H.; Tran-Dube, M. B.U.S. Pat. Appl. U. S. 2006/0046991 A1, 2006.

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