Modification with polysialic acid–PEG copolymer as a new method for improving the therapeutic efficacy of proteins
Author:
Affiliation:
1. Key Laboratory of Food Colloids and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, China
Publisher
Informa UK Limited
Subject
General Medicine,Biochemistry,Biotechnology
Link
https://www.tandfonline.com/doi/pdf/10.1080/10826068.2015.1135463
Reference59 articles.
1. Delivery of Therapeutic Proteins
2. Pegloticase
3. Characterization, efficacy, pharmacokinetics, and biodistribution of 5kDa mPEG modified tetrameric canine uricase variant
4. Improvement of pharmacokinetic, immunological and stability properties of asparaginase by conjugation to linear and branched monomethoxy poly( ethylene glycol)
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