Production of CAR T-cells by GMP-grade lentiviral vectors: latest advances and future prospects

Author:

Poorebrahim Mansour1,Sadeghi Solmaz2,Fakhr Elham3,Abazari Mohammad Foad4,Poortahmasebi Vahdat567,Kheirollahi Asma8,Askari Hassan9,Rajabzadeh Alireza10,Rastegarpanah Malihe1,Linē Aija11,Cid-Arregui Angel212

Affiliation:

1. Department of Medical Biotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran;

2. Recombinant Proteins Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran;

3. Department of Translational Immunology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany;

4. Research Center for Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran;

5. Liver and Gastrointestinal Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran;

6. Infectious and Tropical Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran;

7. Faculty of Medicine, Department of Bacteriology and Virology, Tabriz University of Medical Sciences, Tabriz, Iran;

8. Department of Comparative Biosciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran;

9. Department of Physiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran;

10. Applied Cell Sciences and Tissue Engineering Department, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran;

11. Latvian Biomedical Research and Study Centre, Riga, Latvia;

12. Targeted Tumor Vaccines Group, Clinical Cooperation Unit Applied Tumor Immunity, German Cancer Research Center (DKFZ), Heidelberg, Germany

Publisher

Informa UK Limited

Subject

Biochemistry (medical),Clinical Biochemistry,General Biochemistry, Genetics and Molecular Biology

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