Chemical synthesis and preliminary biological evaluation of C-6-O-methyl-1-deoxynojirimycin as a potent α-glucosidase inhibitor
Author:
Affiliation:
1. School of Chemical Engineering, Nanjing University of Science and Technology, Nanjing, P.R. China;
2. College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, P.R. China
Publisher
Informa UK Limited
Subject
Organic Chemistry,Biochemistry
Link
https://www.tandfonline.com/doi/pdf/10.1080/07328303.2019.1700995
Reference35 articles.
1. Sugar-mimic glycosidase inhibitors: natural occurrence, biological activity and prospects for therapeutic application
2. Nitrogen-in-the-Ring Pyranoses and Furanoses: Structural Basis of Inhibition of Mammalian Glycosidases
3. A New Class of Glucosidase Inhibitor: Analogues of the Naturally Occurring Glucosidase Inhibitor Salacinol with Different Ring Heteroatom Substituents and Acyclic Chain Extension
4. Specificity, inhibition, and synthetic utility of a recombinant human .alpha.-1,3-fucosyltransferase
5. Synthesis of N-substituted iminosugar derivatives and their immunosuppressive activities
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1. Exploring substituent diversity of deoxynojirimycin–triazole hybrid iminosugars: Discovery of potent glucosidase inhibitors;Journal of Carbohydrate Chemistry;2020-10-12
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