Block catiomers with flanking hydrolyzable tyrosinate groups enhance in vivo mRNA delivery via π–π stacking-assisted micellar assembly

Author:

Yang Wenqian12ORCID,Miyazaki Takuya3,Nakagawa Yasuhiro14ORCID,Boonstra Eger1ORCID,Masuda Keita1,Nakashima Yuki1,Chen Pengwen1,Mixich Lucas1,Barthelmes Kevin3,Matsumoto Akira5ORCID,Mi Peng2,Uchida Satoshi6,Cabral Horacio1ORCID

Affiliation:

1. Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan

2. Department of Radiology, Center for Medical Imaging, and State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China

3. Kanagawa Institute of Industrial Science and Technology, Ebina, Japan

4. Department of Materials Science and Engineering, School of Materials and Chemical Technology, Tokyo Institute of Technology, Tokyo, Japan

5. Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo, Japan

6. Graduate School of Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan

Funder

JSPS

Japan Agency for Medical Research and Development

Publisher

Informa UK Limited

Subject

General Materials Science

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