How can we turn the PI3K/AKT/mTOR pathway down? Insights into inhibition and treatment of cancer-Reference-Cited by-同舟云学术

How can we turn the PI3K/AKT/mTOR pathway down? Insights into inhibition and treatment of cancer

Published:2021-04-26 Issue:6 Volume:21 Page:605-619
ISSN:1473-7140
Container-title:Expert Review of Anticancer Therapy
language:en
Short-container-title:Expert Review of Anticancer Therapy

Author:

Afify Said M.¹²,Oo Aung Ko Ko³,Hassan Ghmkin¹⁴,Seno Akimasa¹,Seno Masaharu¹

Affiliation:

1. Department of Biotechnology and Drug Discovery, Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, Okayama, Japan

2. Division of Biochemistry, Chemistry Department, Faculty of Science, Menoufia University, Shebin, El Kom-Menoufia, Egypt

3. Department of Biotechnology, Mandalay Technological University, Mandalay, Myanmar

4. Department of Microbiology and Biochemistry, Faculty of Pharmacy, Damascus University, Damascus, Syria

Funder

funding

Publisher

Informa UK Limited

Subject

Pharmacology (medical),Oncology

Link

https://www.tandfonline.com/doi/pdf/10.1080/14737140.2021.1918001

Reference165 articles.

1. Hallmarks of Cancer: The Next Generation

2. The phosphatidylinositol 3-Kinase–AKT pathway in human cancer

3. The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism

4. Oncogenic PI3K deregulates transcription and translation

5. Up-Regulation of PI 3-Kinases and the Activation of PI3K-Akt Signaling Pathway in Cancer Stem-Like Cells Through DNA Hypomethylation Mediated by the Cancer Microenvironment

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