7-Ketocholesterol accelerates pancreatic β-cell senescence by inhibiting the SIRT1/CDK4–Rb–E2F1 signaling pathway
Author:
Affiliation:
1. Department of Endocrinology and Metabolism, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China
2. Department of Endocrinology, Haining People’s Hospital, Haining, China
Funder
National Natural Science Foundation of China
the National Key Technology R&D Program of China
Zhejiang Provincial Natural Science Foundation of China
Publisher
Informa UK Limited
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism
Link
https://www.tandfonline.com/doi/pdf/10.1080/19382014.2023.2219105
Reference47 articles.
1. Aging and stress induced β cell senescence and its implication in diabetes development
2. Age-associated changes of islet endocrine cells and the effects of body mass index in Japanese
3. Inflamm-aging: An Evolutionary Perspective on Immunosenescence
4. The endoplasmic reticulum stress/autophagy pathway is involved in cholesterol-induced pancreatic β-cell injury
5. Lipids as Regulators of Cellular Senescence
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