The endoplasmic reticulum stress/autophagy pathway is involved in cholesterol-induced pancreatic β-cell injury
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep44746.pdf
Reference27 articles.
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3. Zhou, J., Wu, J., Zheng, F., Jin, M. & Li, H. Glucagon-like peptide-1 analog-mediated protection against cholesterol-induced apoptosis via mammalian target of rapamycin activation in pancreatic betaTC-6 cells -1. J Diabetes 7, 231–239 (2015).
4. Lupi, R. et al. Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated. Diabetes 51, 1437–1442 (2002).
5. Prentki, M. & Nolan, C. J. Islet beta cell failure in type 2 diabetes. J Clin Invest 116, 1802–1812 (2006).
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