Computer-aided design and synthesis of 3-carbonyl-5-phenyl-1H-pyrazole as highly selective and potent BRAFV600E and CRAF inhibitor-Reference-Cited by-同舟云学术

Computer-aided design and synthesis of 3-carbonyl-5-phenyl-1H-pyrazole as highly selective and potent BRAFV600E and CRAF inhibitor

Published:2019-01-01 Issue:1 Volume:34 Page:1314-1320
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Kim Jinwoong¹,Choi Byeongha¹,Im Daseul¹,Jung Hoyong¹,Moon Hyungwoo¹,Aman Waqar²,Hah Jung-Mi¹

Affiliation:

1. Department of Pharmacy and Institute of Pharmaceutical Science and Technology, College of Pharmacy, Hanyang University, Ansan, Gyunggido, Republic of Korea;

2. Kohat University of Science and Technology, Kohat, Khyber Pukhtunkhwa, Pakistan

Funder

National Research Foundation of Korea

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://tandfonline.com/doi/pdf/10.1080/14756366.2019.1599366

Reference20 articles.

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2. Current Insights of BRAF Inhibitors in Cancer

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4. Structural Investigation of B-Raf Paradox Breaker and Inducer Inhibitors

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