Structural Investigation of B-Raf Paradox Breaker and Inducer Inhibitors-Reference-Cited by-同舟云学术

Structural Investigation of B-Raf Paradox Breaker and Inducer Inhibitors

Published:2015-02-10 Issue:4 Volume:58 Page:1818-1831
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Arora Rohit¹,Di Michele Michela²³,Stes Elisabeth²³,Vandermarliere Elien²³,Martens Lennart²³,Gevaert Kris²³,Van Heerde Erika⁴,Linders Joannes T. M.⁴,Brehmer Dirk⁴,Jacoby Edgar⁴,Bonnet Pascal¹

Affiliation:

1. Institut de Chimie Organique et Analytique, UMR CNRS-Université d’Orléans 7311, Université d’Orléans BP 6759, Orléans 45067 Cedex 2, France

2. Department of Medical Protein Research, VIB, Ghent B-9000, Belgium

3. Department of Biochemistry, Ghent University, Ghent B-9000, Belgium

4. Janssen Research and Development, a division of Janssen Pharmaceutica N.V., Turnhoutseweg 30, Beerse 2340, Belgium

Funder

Fonds Wetenschappelijk Onderzoek

Agentschap voor Innovatie door Wetenschap en Technologie

Janssen Pharmaceutica NV

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm501667n

Reference42 articles.

1. Mitogen-activated protein kinase pathways

2. Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions

3. The complexity of Raf-1 regulation

4. Mutations of the BRAF gene in human cancer

5. Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma

Cited by 37 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Targeting CRAF kinase in anti-cancer therapy: progress and opportunities;Molecular Cancer;2023-12-18

2. Targeting RAF Isoforms and Tumor Microenvironments in RAS or BRAF Mutant Colorectal Cancers with SJ-C1044 for Anti-Tumor Activity;Current Issues in Molecular Biology;2023-07-13

3. Selected Approaches to Disrupting Protein–Protein Interactions within the MAPK/RAS Pathway;International Journal of Molecular Sciences;2023-04-17

4. Design, synthesis and characterisation of a novel type II B-RAF paradox breaker inhibitor;European Journal of Medicinal Chemistry;2023-03

5. A Perspective Study on the RTK, PI3K, B‐Raf, CDK and the Multi‐Protein Targeting in Medicinal Chemistry;Chemistry & Biodiversity;2022-10