Design and biological evaluation of 3-substituted quinazoline-2,4(1 <i>H</i> ,3 <i>H</i> )-dione derivatives as dual c-Met/VEGFR-2-TK inhibitors-Reference-Cited by-同舟云学术

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Design and biological evaluation of 3-substituted quinazoline-2,4(1 H ,3 H )-dione derivatives as dual c-Met/VEGFR-2-TK inhibitors

Published:2023-03-15 Issue:1 Volume:38 Page:
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Hassan Abdelfattah¹^ORCID,Mubarak Fawzy A. F.²,Shehadi Ihsan A.³,Mosallam Ahmed M.²,Temairk Hussain²,Badr Mohamed⁴^ORCID,Abdelmonsef Aboubakr H.²

Affiliation:

1. Department of Medicinal Chemistry, Faculty of Pharmacy, South Valley University, Qena, Egypt

2. Department of Chemistry, Faculty of Science, South Valley University, Qena, Egypt

3. Department of Chemistry, College of Sciences, Pure and Applied Chemistry Research Group, University of Sharjah, Sharjah, United Arab Emirates

4. Department of Biochemistry, Faculty of Pharmacy, Menoufia University, Menoufia, Egypt

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/14756366.2023.2189578

Reference59 articles.

1. Global Cancer Observatory. Cancer today. Lyon: International Agency for Research on Cancer; 2022. https://gco.iarc.fr/

2. Design, synthesis and biological evaluation of 7H-pyrrolo[2,3-d]pyrimidine derivatives containing 1,8-naphthyridine-4-one fragment

3. Recent advances in the development of dual VEGFR and c-Met small molecule inhibitors as anticancer drugs

4. Discovery of N-substituted-3-phenyl-1,6-naphthyridinone derivatives bearing quinoline moiety as selective type II c-Met kinase inhibitors against VEGFR-2

5. Design, synthesis and biological evaluation of 4-aminopyrimidine-5-cabaldehyde oximes as dual inhibitors of c-Met and VEGFR-2

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