Further validation of strecker-type α-aminonitriles as a new class of potent human carbonic anhydrase II inhibitors: hit expansion within the public domain using differential scanning fluorimetry leads to chemotype refinement-Reference-Cited by-同舟云学术

Further validation of strecker-type α-aminonitriles as a new class of potent human carbonic anhydrase II inhibitors: hit expansion within the public domain using differential scanning fluorimetry leads to chemotype refinement

Published:2019-11-22 Issue:1 Volume:35 Page:165-171
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Krasavin Mikhail¹,Kalinin Stanislav¹,Zozulya Sergey²³,Griniukova Anastasia²,Borysko Petro²,Angeli Andrea⁴^ORCID,Supuran Claudiu T.⁴^ORCID

Affiliation:

1. Saint Petersburg State University, Saint Petersburg, Russian Federation

2. Enamine Ltd, Kyiv, Ukraine

3. Taras Shevchenko National University, Kyiv, Ukraine

4. Neurofarba Department, Universita degli Studi di Firenze, Florence, Italy

Funder

Russian Federation Government Megagrant

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/14756366.2019.1693556

Reference16 articles.

1. Universal Screening Methods and Applications of ThermoFluor®

2. The screening and the building block collection of Enamine, Ltd. can be obtained at https://www.enaminestore.com/catalog

3. Discovery of Strecker-type α-aminonitriles as a new class of human carbonic anhydrase inhibitors using differential scanning fluorimetry

4. Carbonic Anhydrase Inhibitors:N-Cyanosulfonamides, a new Class of High Affinity Isozyme II and IV Inhibitors

5. Probing the ‘bipolar’ nature of the carbonic anhydrase active site: Aromatic sulfonamides containing 1,3-oxazol-5-yl moiety as picomolar inhibitors of cytosolic CA I and CA II isoforms

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Synthesis and biological evaluation of Au‐NHC complexes;Applied Organometallic Chemistry;2022-07-19

2. QM and QM/MM study on inhibition mechanism of polyphenolic compounds as non-classical inhibitors of α-human carbonic anhydrase (II);Theoretical Chemistry Accounts;2021-09-22

3. The (NHC)PdBr2(2-aminopyridine) complexes: synthesis, characterization, molecular docking study, and inhibitor effects on the human serum carbonic anhydrase and serum bovine xanthine oxidase;Monatshefte für Chemie - Chemical Monthly;2020-10

4. Quantum mechanical study of human carbonic anhydrase II in complex with polyamines as novel inhibitors: Kinetic and thermodynamic investigation;Computational and Theoretical Chemistry;2020-09