Exhaustive CoMFA and CoMSIA analyses around different chemical entities: a ligand-based study exploring the affinity and selectivity profiles of 5-HT1A ligands-Reference-Cited by-同舟云学术

Exhaustive CoMFA and CoMSIA analyses around different chemical entities: a ligand-based study exploring the affinity and selectivity profiles of 5-HT1A ligands

Published:2017-01-01 Issue:1 Volume:32 Page:214-230
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Guariento Sara¹,Franchini Silvia²,Tonelli Michele¹,Fossa Paola¹,Sorbi Claudia²,Cichero Elena¹,Brasili Livio²

Affiliation:

1. Department of Pharmacy, University of Genoa, Genoa, Italy;

2. Department of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/14756366.2016.1247057

Reference31 articles.

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2. BMY 7378, a buspirone analog with high affinity, selectivity and low intrinsic activity at the 5-HT1A receptor in rat and guinea pig hippocampal membranes

3. The 5-HT1A receptor and its ligands: structure and function

4. Selectively Bred Lines of Rats Differ in Social Interaction and Hippocampal 5-HT1A Receptor Function: A Link Between Anxiety and Depression?

5. Novel 5-HT1A-receptor agonists: F11440, MKC242 and BAYx3702

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