Latency, thermal stability, and identification of an inhibitory compound of mirolysin, a secretory protease of the human periodontopathogen Tannerella forsythia

Author:

Zak Krzysztof M.12ORCID,Bostock Mark J.13ORCID,Waligorska Irena4,Thøgersen Ida B.5,Enghild Jan J.5,Popowicz Grzegorz M.13,Grudnik Przemyslaw2,Potempa Jan46ORCID,Ksiazek Miroslaw46ORCID

Affiliation:

1. Helmholtz Zentrum München, Institute of Structural Biology, Neuherberg, Germany

2. Malopolska Centre of Biotechnology, Jagiellonian University, Kraków, Poland

3. Biomolecular NMR and Center for Integrated Protein Science Munich at Department Chemie, Technical University of Munich, Garching, Germany

4. Department of Microbiology, Faculty of Biochemistry, Biophysics, and Biotechnology, Jagiellonian University, Krakow, Poland

5. Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark

6. Department of Oral Immunology and Infectious Diseases, University of Louisville School of Dentistry, Louisville, KY, USA

Funder

National Science Center, Poland

Polish Ministry of Science and Higher Education

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

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