1-Oxo-3,4-dihydroisoquinoline-4-carboxamides as novel druglike inhibitors of poly(ADP-ribose) polymerase (PARP) with favourable ADME characteristics-Reference-Cited by-同舟云学术

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1-Oxo-3,4-dihydroisoquinoline-4-carboxamides as novel druglike inhibitors of poly(ADP-ribose) polymerase (PARP) with favourable ADME characteristics

Published:2021-01-01 Issue:1 Volume:36 Page:1968-1983
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Safrygin Alexander¹,Zhmurov Petr¹,Dar’in Dmitry¹,Silonov Sergey²,Kasatkina Mariia²,Zonis Yulia²,Gureev Maxim³^ORCID,Krasavin Mikhail¹⁴

Affiliation:

1. Saint Petersburg State University, Saint Petersburg, Russian Federation

2. JSC BIOCAD, Saint Petersburg, Russian Federation

3. Digital Biodesign and Personalized Healthcare Research Center, Sechenov First Moscow State Medical University, Moscow, Russian Federation

4. Immanuel Kant Baltic Federal University, Kaliningrad, Russian Federation

Funder

Russian Foundation for Basic Research

Ministry of Science and Higher Education of the Russian Federation

Saint Petersburg State University

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/14756366.2021.1972993

Reference22 articles.

1. Cell Cycle and Cancer

2. New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs

3. A decade of clinical development of PARP inhibitors in perspective

4. Discovery of 2-[1-(4,4-Difluorocyclohexyl)piperidin-4-yl]-6-fluoro-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide (NMS-P118): A Potent, Orally Available, and Highly Selective PARP-1 Inhibitor for Cancer Therapy

5. Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Efficient and scalable synthesis of 3,4-dihydroisoquinolin-1(2H)-ones by benzylic oxidation of tetrahydroisoquinoline derivatives using cerium ammonium nitrate (CAN);Organic & Biomolecular Chemistry;2024

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