Phenyl-substituted aminomethylene-bisphosphonates inhibit human P5C reductase and show antiproliferative activity against proline-hyperproducing tumour cells
Author:
Affiliation:
1. Department of Life Science and Biotechnology, University of Ferrara, Ferrara, Italy
2. Department of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, Ferrara, Italy
Funder
University of Ferrara
Publisher
Informa UK Limited
Subject
Drug Discovery,Pharmacology,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/14756366.2021.1919890
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1. Targeting Metabolism for Cancer Therapy
2. Metabolic pathway analyses identify proline biosynthesis pathway as a promoter of liver tumorigenesis
3. Pyrroline-5-carboxylate reductase 1 (PYCR1) upregulation contributes to gastric cancer progression and indicates poor survival outcome
4. Proline Metabolism in Tumor Growth and Metastatic Progression
5. Proline Metabolism in Cell Regulation and Cancer Biology: Recent Advances and Hypotheses
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