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Targeting Metabolism for Cancer Therapy

Published:2017-09 Issue:9 Volume:24 Page:1161-1180
ISSN:2451-9456
Container-title:Cell Chemical Biology
language:en
Short-container-title:Cell Chemical Biology

Author:

Luengo Alba,Gui Dan Y.,Vander Heiden Matthew G.

Funder

Lustgarten Foundation

SU2C

Ludwig Center

NCI

HHMI

Ludwig Center for Molecular Oncology

NSF

NIH

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,Biochemistry

Reference280 articles.

1. A role for cytosolic fumarate hydratase in urea cycle metabolism and renal neoplasia;Adam;Cell Rep.,2013

2. From Krebs to clinic: glutamine metabolism to cancer therapy;Altman;Nat. Rev. Cancer,2016

3. Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis;Anastasiou;Nat. Chem. Biol.,2012

4. Up-regulation of asparagine synthetase expression is not linked to the clinical response L-asparaginase in pediatric acute lymphoblastic leukemia;Appel;Blood,2006

5. Phenformin as prophylaxis and therapy in breast cancer xenografts;Appleyard;Br. J. Cancer,2012

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