Anticancer activity and toxicity of new quaternary ammonium geldanamycin derivative salts and their mixtures with potentiators-Reference-Cited by-同舟云学术

Anticancer activity and toxicity of new quaternary ammonium geldanamycin derivative salts and their mixtures with potentiators

Published:2021-01-01 Issue:1 Volume:36 Page:1898-1904
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Skrzypczak Natalia¹,Pyta Krystian¹,Ruszkowski Piotr²,Mikołajczak Przemysław²,Kucińska Małgorzata³,Murias Marek³,Gdaniec Maria¹,Bartl Franz⁴,Przybylski Piotr¹

Affiliation:

1. Faculty of Chemistry, Adam Mickiewicz University, Poznan, Poland

2. Department of Pharmacology, Poznan University of Medical Sciences, Poznan, Poland

3. Department of Toxicology, Poznan University of Medical Sciences, Poznań, Poland

4. Lebenswissenschaftliche Fakultät, Institutfür Biologie, Biophysikalische Chemie Humboldt-Universität zu Berlin Invalidenstrasse 42, Berlin, Germany

Funder

Polish National Science Centre

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/14756366.2021.1960829

Reference49 articles.

1. Production of 17-O-demethyl-geldanamycin, a cytotoxic ansamycin polyketide, by Streptomyces hygroscopicus DEM20745

2. Targeting heat-shock-protein 90 (Hsp90) by natural products: geldanamycin, a show case in cancer therapy

3. Geldanamycin and its anti-cancer activities