Synthesis, antitumour activities and molecular docking of thiocarboxylic acid ester-based NSAID scaffolds: COX-2 inhibition and mechanistic studies-Reference-Cited by-同舟云学术

Synthesis, antitumour activities and molecular docking of thiocarboxylic acid ester-based NSAID scaffolds: COX-2 inhibition and mechanistic studies

Published:2018-01-01 Issue:1 Volume:33 Page:989-998
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

El-Azab Adel S.¹²^ORCID,Abdel-Aziz Alaa A.-M.¹³^ORCID,Abou-Zeid Laila A.⁴,El-Husseiny Walaa M.⁴,El_Morsy Ahmad M.²,El-Gendy Manal A.¹,El-Sayed Magda A.-A.⁴⁵^ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia;

2. Department of Organic Chemistry, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt;

3. Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt;

4. Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt;

5. Department of Pharmaceutical Chemistry, Faculty of pharmacy, Horus university, New Damietta, Egypt

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/14756366.2018.1474878

Reference60 articles.

1. Comparing Adult and Pediatric Rhabdomyosarcoma in the Surveillance, Epidemiology and End Results Program, 1973 to 2005: An Analysis of 2,600 Patients

2. Enhancement of chemotherapeutic drug toxicity to human tumour cells in vitro by a subset of non-steroidal anti-inflammatory drugs (NSAIDs)

3. Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas

4. COX-2: A Molecular Target for Colorectal Cancer Prevention

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