Design and synthesis of novel 7-[(N-substituted-thioureidopiperazinyl)-methyl]-camptothecin derivatives as potential cytotoxic agents-Reference-Cited by-同舟云学术

Design and synthesis of novel 7-[(N-substituted-thioureidopiperazinyl)-methyl]-camptothecin derivatives as potential cytotoxic agents

Published:2019-02-20 Issue:14 Volume:34 Page:2022-2029
ISSN:1478-6419
Container-title:Natural Product Research
language:en
Short-container-title:Natural Product Research

Author:

Song Zi-Long¹,Yang Guan-Zhou¹,Li Jun-Cai¹,Liu Ying-Qian¹,Yang Chen-Jie¹,Goto Masuo²,Zhang Zhi-Jun¹^ORCID,Morris-Natschke Susan L.²,Liu Hua¹,Lee Kuo-Hsiung²³

Affiliation:

1. School of Pharmacy, Lanzhou University, Lanzhou, P.R. China;

2. Natural Products Research Laboratories, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina, USA;

3. Chinese Medicine Research and Development Center, China Medical University and Hospital, Taichung, Taiwan

Funder

National Natural Science Foundation of China

Key Program for international S&T cooperation projects of China Gansu Province

National Key Research and Development Program of China

Fundamental Research Funds for the Central Universities

Health and Welfare Surcharge of Tobacco Products, China Medical University Hospital Cancer Research Center of Excellence

Publisher

Informa UK Limited

Subject

Organic Chemistry,Plant Science,Biochemistry,Analytical Chemistry

Link

https://www.tandfonline.com/doi/pdf/10.1080/14786419.2019.1573231

Reference32 articles.

1. Chemistry of the Camptothecins in the Bloodstream.

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3. Gimatecan exerts potent antitumor activity against gastric cancer in vitro and in vivo via AKT and MAPK signaling pathways

4. Novel 7-Substituted Camptothecins with Potent Antitumor Activity

5. Novel cytotoxic 7-iminomethyl and 7-aminomethyl derivatives of camptothecin

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