Naturally occurring organosulfur compounds effectively inhibits PCSK-9 activity and restrict PCSK-9-LDL-receptor interaction via <i>in-silico</i> and <i>in-vitro</i> approach-Reference-Cited by-同舟云学术

Naturally occurring organosulfur compounds effectively inhibits PCSK-9 activity and restrict PCSK-9-LDL-receptor interaction via in-silico and in-vitro approach

Published:2023-10-16 Issue: Volume: Page:1-10
ISSN:1478-6419
Container-title:Natural Product Research
language:en
Short-container-title:Natural Product Research

Author:

Ahmad Parvej¹,Alvi Sahir S.²,Waiz Mohd¹,Khan Mohd Shahnawaz³,Ahmad Saheem⁴,Khan M. Salman¹

Affiliation:

1. IIRC-5, Clinical Biochemistry and Natural Product Research Lab, Department of Biosciences, Integral University, Lucknow, Uttar Pradesh, India

2. Department of Immunology and Microbiology, South TX Center of Excellence in Cancer Research, School of Medicine, University of Texas Rio Grande Valley, McAllen, Texas, USA

3. Department of Biochemistry, College of Science, King Saud University, Kingdom of Saudi Arabia

4. Department of Medical Laboratory Sciences, College of Applied Medical Sciences, University of Hail, Hail, Saudi Arabia

Funder

the Research Supporting Project

King Saud University, Riyadh, Kingdom of Saudi Arabia. The author also acknowledges DHR for young scientist research grant

Publisher

Informa UK Limited

Subject

Organic Chemistry,Plant Science,Biochemistry,Analytical Chemistry

Link

https://www.tandfonline.com/doi/pdf/10.1080/14786419.2023.2269465

Reference33 articles.

1. Insights into pharmacological mechanisms of polydatin in targeting risk factors-mediated atherosclerosis

2. Identification and evaluation of natural organosulfur compounds as potential dual inhibitors of α-amylase and α-glucosidase activity: an in-silico and in-vitro approach

3. Target-Based Virtual and Biochemical Screening Against HMG-CoA Reductase Reveals Allium sativum-Derived Organosulfur Compound N-Acetyl Cysteine as a Cardioprotective Agent

4. Functioning of Organosulfur Compounds from Garlic (Allium sativum Linn) in Targeting Risk Factor-Mediated Atherosclerosis: A Cross Talk Between Alternative and Modern Medicine

5. Hepatoprotective and antiapoptotic role of aged black garlic against hepatotoxicity induced by cyclophosphamide

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Organosulfur Compounds, S‐Allyl‐L‐Cysteine and S‐Ethyl‐L‐Cysteine, Target PCSK‐9/LDL‐R‐Axis to Ameliorate Cardiovascular, Hepatic, and Metabolic Changes in High Carbohydrate and High Fat Diet‐Induced Metabolic Syndrome in Rats;Phytotherapy Research;2024-09-03