Target-Based Virtual and Biochemical Screening Against HMG-CoA Reductase Reveals Allium sativum-Derived Organosulfur Compound N-Acetyl Cysteine as a Cardioprotective Agent-Reference-Cited by-同舟云学术

Target-Based Virtual and Biochemical Screening Against HMG-CoA Reductase Reveals Allium sativum-Derived Organosulfur Compound N-Acetyl Cysteine as a Cardioprotective Agent

Published:2022-10-27 Issue:6 Volume:32 Page:962-973
ISSN:1981-528X
Container-title:Revista Brasileira de Farmacognosia
language:en
Short-container-title:Rev. Bras. Farmacogn.

Author:

Ahmad Parvej^ORCID,Alvi Sahir Sultan^ORCID,Iqbal Johar^ORCID,Khan M. Salman^ORCID

Funder

DHR

Publisher

Springer Science and Business Media LLC

Subject

General Pharmacology, Toxicology and Pharmaceutics

Link

https://link.springer.com/content/pdf/10.1007/s43450-022-00330-1.pdf

Reference50 articles.

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2. Ahmad P, Alvi SS, Khan MS (2019) Functioning of organosulfur compounds from garlic (Allium sativum Linn) in targeting risk factor-mediated atherosclerosis: a cross talk between alternative and modern medicine. In: Akhta MS, Swamy MK, Sinniah UR (eds), Natural Bio-Active Compounds. Springer Singapore, pp 561–585. https://doi.org/10.1007/978-981-13-7154-7_20

3. Ahmad P, Alvi SS, Johar I, Khan MS (2021) Identification and evaluation of natural organosulfur compounds as potential dual inhibitors of α-amylase and α-glucosidase activity: an in-silico and in-vitro approach. Med Chem Res 30:2184–2202. https://doi.org/10.1007/s00044-021-02799-2

4. Ahmad S, Nabi R, Alvi SS, Khan M, Khan S, Khan MY, Hussain I, Shahanawaz SD, Khan MS (2022) Carvacrol protects against carbonyl osmolyte-induced structural modifications and aggregation to serum albumin: insights from physicochemical and molecular interaction studies. Int J Biol Macromol 213:663–674. https://doi.org/10.1016/j.ijbiomac.2022.05.198

5. Akhter F, Alvi SS, Ahmad P, Iqbal D, Alshehri BM, Khan MS (2019) Therapeutic efficacy of Boerhaavia diffusa (Linn) root methanolic extract in attenuating streptozotocin-induced diabetes, diabetes-linked hyperlipidemia and oxidative-stress in rats. Biomed Res Ther 6:3293–3306. https://doi.org/10.15419/bmrat.v6i7.556

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