Development of a Species-Specific Model of Cerebral Hemodynamics-Reference-Cited by-同舟云学术

Development of a Species-Specific Model of Cerebral Hemodynamics

Published:2005 Issue:3 Volume:6 Page:181-195
ISSN:1027-3662
Container-title:Journal of Theoretical Medicine
language:en
Short-container-title:Journal of Theoretical Medicine

Author:

Daun Silvia¹,Tjardes Thorsten²^ORCID

Affiliation:

1. Department of Mathematics, University of Cologne, Weyertal 86-90, Cologne D-50931, Germany

2. Department of Trauma and Orthopaedic Surgery, University of Witten-Herdecke, Merheim Medical Center, Ostmerheimerstr. 200, Cologne D-51109, Germany

Abstract

In this paper, a mathematical model for the description of cerebral hemodynamics is developed. This model is able to simulate the regulation mechanisms working on the small cerebral arteries and arterioles, and thus to adapt dynamically the blood flow in brain. Special interest is laid on the release of catecholamines and their effect on heart frequency, cardiac output and blood pressure. Therefore, this model is able to describe situations of severe head injuries in a very realistic way.

Publisher

Hindawi Limited

Subject

General Biochemistry, Genetics and Molecular Biology

Link

http://downloads.hindawi.com/journals/cmmm/2005/873836.pdf

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