Accelerator-based boron neutron capture therapy for malignant glioma: a pilot neutron irradiation study using boron phenylalanine, sodium borocaptate and liposomal borocaptate with a heterotopic U87 glioblastoma model in SCID mice

Author:

Zavjalov Evgenii12ORCID,Zaboronok Alexander13ORCID,Kanygin Vladimir1,Kasatova Anna14,Kichigin Aleksandr1ORCID,Mukhamadiyarov Rinat15ORCID,Razumov Ivan12,Sycheva Tatiana4ORCID,Mathis Bryan J.3ORCID,Maezono Sakura Eri B.6ORCID,Matsumura Akira3ORCID,Taskaev Sergey47ORCID

Affiliation:

1. Laboratory of medical and biological problems of BNCT, Novosibirsk State University, Novosibirsk, Russia;

2. Center for Genetic Resources of Laboratory Animals, Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia;

3. Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan;

4. Budker Institute of Nuclear Physics, Novosibirsk, Russia;

5. Research Institute for Complex Issues of Cardiovascular Diseases SB RAS, Kemerovo, Russia

6. PhD Program in Human Biology, School of Integrative and Global Majors and International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Tsukuba, Ibaraki, Japan;

7. Laboratory of BNCT, Novosibirsk State University, Novosibirsk, Russia;

Publisher

Informa UK Limited

Subject

Radiology Nuclear Medicine and imaging,Radiological and Ultrasound Technology

Reference42 articles.

1. Boron delivery agents for neutron capture therapy of cancer

2. A realistic appraisal of boron neutron capture therapy as a cancer treatment modality

3. Neutron producing target for accelerator based neutron capture therapy

4. Brednikhin SA, Lezhnin SI, Frolov SA, Yurov DM. 2012. [NMC code for statistical modeling of neutron transport in fissionable media. Validation and applications]. Moscow: IBRAE. Russian Academy of Sciences, Institute of Problems of Safety, Development of Atomic Energy. No. IBRAE-2012-04.

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