ASCT2: a potential cancer drug target
Author:
Affiliation:
1. Translational Cancer Metabolism Laboratory, School of Medical Sciences and Prince of Wales Clinical School, UNSW Sydney, Australia
Funder
Cancer Council NSW
Movember Foundation
Publisher
Informa UK Limited
Subject
Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/14728222.2019.1627328
Reference29 articles.
1. The role of ASCT2 in cancer: A review
2. The Human SLC1A5 (ASCT2) Amino Acid Transporter: From Function to Structure and Role in Cell Biology
3. Ablation of the ASCT2 (SLC1A5) gene encoding a neutral amino acid transporter reveals transporter plasticity and redundancy in cancer cells
4. Cysteine is not a substrate but a specific modulator of human ASCT2 (SLC1A5) transporter
5. Targeting SLC1a5-mediated glutamine dependence in non-small cell lung cancer
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