Can mutagenicity information be useful in an Integrated Testing Strategy (ITS) for skin sensitization?

Author:

Patlewicz G.1,Mekenyan O.2,Dimitrova G.2,Kuseva C.2,Todorov M.2,Kotov S.2,Stoeva S.2,Donner E.M.1

Affiliation:

1. a DuPont Haskell Global Centers for Health and Environmental Sciences , Newark, Delaware, USA

2. b Laboratory of Mathematical Chemistry , University As Zlatarov , Bourgas, Bulgaria

Publisher

Informa UK Limited

Subject

Drug Discovery,Molecular Medicine,General Medicine,Bioengineering

Reference129 articles.

1. 3.3. Eye Irritation

2. http://guidance.echa.europa.eu/docs/guidance_document/information_requirements_en.htm (accessed 12 May 2010)

3. G. Patlewicz and A. Worth,Review of Data Sources, QSARs and Integrated Testing Strategies for Skin Sensitisation, EUR 23225 EN. (2008). Available at http://ecb.jrc.ec.europa.eu/qsar/publications/

4. What makes a chemical an allergen?

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