Integrated approach to testing and assessment for predicting rodent genotoxic carcinogenicity

Author:

Petkov Petko I.1,Schultz Terry W.2,Donner E. Maria3,Honma Masamitsu4,Morita Takeshi5,Hamada Shuichi6,Wakata Akihiro7,Mishima Masayuki8,Maniwa Jiro9,Todorov Milen1,Kaloyanova Elena1,Kotov Stefan1,Mekenyan Ovanes G.1

Affiliation:

1. Laboratory of Mathematical Chemistry (LMC); As. Zlatarov University; Bourgas Bulgaria

2. College of Veterinary Medicine; The University of Tennessee; Knoxville TN 37996-4500 USA

3. DuPont Haskell Global Centers for Health and Environmental Sciences, Newark; DE USA

4. Division of Genetics and Mutagenesis; National Institute of Health Sciences; Tokyo Japan

5. Division of Risk Assessment; National Institute of Health Sciences; Tokyo Japan

6. LSI Medience Corporation; Ibaraki Japan

7. Astellas Pharma Inc; Osaka Japan

8. Chugai Pharmaceutical Co., Ltd., Fuji Gotemba Research Labs; Shizuoka Japan

9. Clinical Science Division, Research & Development AstraZeneca KK; Osaka Japan

Publisher

Wiley

Subject

Toxicology

Reference63 articles.

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2. Cytogenetic toxicity of gentian violet and crystal violet on mammalian cells in vitro;Au;Mutat. Res.,1978

3. Bahler D Bristol DW 1993 A quantitative comparison of the utility of characteristics for predicting chemical carcinogenesis. 4th Annual Keck Symposium on Computational Biology, Pittsburgh

4. The aryl hydrocarbon receptor complex and the control of gene expression;Beischlag;Crit. Rev. Eukaryot. Gene Expr.,2008

5. Predicting the carcinogenicity of chemicals with alternative approaches;Benigni;Expert Opin. Drug Metab. Toxicol.,2014

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