Evaluation of the OECD (Q)SAR Application Toolbox and Toxtree for predicting and profiling the carcinogenic potential of chemicals

Author:

Mombelli E.1,Devillers J.2

Affiliation:

1. a Unité Modèles pour l'Ecotoxicologie et la Toxicologie (METO), Institut National de l'Environnement Industriel et des Risques (INERIS) , Verneuil en Halatte, France

2. b CTIS , Rillieux La Pape, France

Publisher

Informa UK Limited

Subject

Drug Discovery,Molecular Medicine,General Medicine,Bioengineering

Reference37 articles.

1. The History of Cancer Research: Introducing an AACR Centennial Series

2. Regulation (EC) No 1907/2006 of the European Parliament and of the Council of 18 December 2006 concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH), establishing a European Chemicals Agency, amending Directive 1999/45/EC and repealing Council Regulation (EEC) No 793/93 and Commission Regulation (EC) No 1488/94 as well as Council Directive 76/769/EEC and Commission Directives 91/155/EEC, 93/67/EEC, 93/105/EC and 2000/21/EC, The European Parliament and the Council of the European Union, 2006. Available at http://eur-lex.europa.eu/LexUriServ/site/en/oj/2006/l_396/l_39620061230en00010849.pdf (last accessed 21 May 2010)

3. ECVAM – overview - European Centre for the Validation of Alternative Methods. Available at http://ec.europa.eu/dgs/jrc/downloads/jrc_press_animal_ecvam_overview.pdf (last accessed 21 May 2010)

4. AI and SAR approaches for predicting chemical carcinogenicity: Survey and status report

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