Inhibitory effect of 13 taxane diterpenoids from Chinese yew (Taxus chinensis var. mairei) on the proliferation of HeLa cervical cancer cells-Reference-Cited by-同舟云学术

Inhibitory effect of 13 taxane diterpenoids from Chinese yew (Taxus chinensis var. mairei) on the proliferation of HeLa cervical cancer cells

Published:2016-10-02 Issue:10 Volume:80 Page:1883-1886
ISSN:0916-8451
Container-title:Bioscience, Biotechnology, and Biochemistry
language:en
Short-container-title:

Author:

Liu Hai-Sheng¹,Gao Yu-Huan¹,Liu Li-Hong¹,Liu Wei²,Shi Qing-Wen³,Dong Mei³,Suzuki Toshikazu⁴,Kiyota Hiromasa⁵

Affiliation:

1. Department of Hematology, Fourth Hospital of Hebei Medical University, Shijiazhuang, China

2. Department of Medical Oncology, Fourth Hospital of Hebei Medical University, Shijiazhuang, China

3. Department of Forensic Medicine, Hebei Medical University, Shijiazhuang, China

4. Department of Health and Nutrition, Wayo Women’s University, Ichikawa, Japan

5. Graduate School of Environmental & Life Science, Okayama University, Okayama, Japan

Abstract

Abstract The inhibitory effect of 13 taxanes isolated from the Chinese yew (Taxus chinensis var. mairei) on the proliferation of human cervical cancer HeLa cells were examined using an MTT assay. Four compounds having a hydrophobic cinnamate side chain showed antiproliferative activity, which may be due to increased cell permeability.

Funder

Science and Technology Research Projects of Hebei Educational Committee

JSPS KAKENHI

Publisher

Oxford University Press (OUP)

Subject

Organic Chemistry,Molecular Biology,Applied Microbiology and Biotechnology,General Medicine,Biochemistry,Analytical Chemistry,Biotechnology

Link

http://academic.oup.com/bbb/article-pdf/80/10/1883/36833075/bbb1883.pdf

Reference12 articles.

1. Constituents from Salvia species and their biological activities;Ni;Chem. Rev,2012

2. New natural taxane diterpenoids from Taxus species since 1999;Shi;Chem. Biodivers,2005