FR-900098, an antimalarial development candidate that inhibits the non-mevalonate isoprenoid biosynthesis pathway, shows no evidence of acute toxicity and genotoxicity-Reference-Cited by-同舟云学术

FR-900098, an antimalarial development candidate that inhibits the non-mevalonate isoprenoid biosynthesis pathway, shows no evidence of acute toxicity and genotoxicity

Published:2016-06-03 Issue:6 Volume:7 Page:718-728
ISSN:2150-5594
Container-title:Virulence
language:en
Short-container-title:Virulence

Author:

Wiesner Jochen,Ziemann Christina,Hintz Martin,Reichenberg Armin,Ortmann Regina,Schlitzer Martin,Fuhst Rainer,Timmesfeld Nina,Vilcinskas Andreas,Jomaa Hassan

Publisher

Informa UK Limited

Subject

Infectious Diseases,Microbiology (medical),Immunology,Microbiology,Parasitology

Link

https://tandfonline.com/doi/pdf/10.1080/21505594.2016.1195537

Reference39 articles.

1. The Plastid-Like Organelle of Apicomplexan Parasites as Drug Target

2. Fosmidomycin, a specific inhibitor of 1-deoxy-d-xylulose 5-phosphate reductoisomerase in the nonmevalonate pathway for terpenoid biosynthesis

3. Inhibition of the Non-Mevalonate 1-Deoxy-ᴅ-xylulose-5-phosphate Pathway of Plant Isoprenoid Biosynthesis by Fosmidomycin

4. Inhibitors of the Nonmevalonate Pathway of Isoprenoid Biosynthesis as Antimalarial Drugs

5. Molecular Epidemiology of Malaria in Cameroon. XXV. In Vitro Activity of Fosmidomycin and its Derivatives against Fresh Clinical Isolates of Plasmodium falciparum and Sequence Analysis of 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase

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