An AKR1C3-specific prodrug with potent anti-tumor activities against T-ALL-Reference-Cited by-同舟云学术

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An AKR1C3-specific prodrug with potent anti-tumor activities against T-ALL

Published:2020-02-24 Issue:7 Volume:61 Page:1660-1668
ISSN:1042-8194
Container-title:Leukemia & Lymphoma
language:en
Short-container-title:Leukemia & Lymphoma

Author:

Wang Yanlan¹,Liu Yue¹,Zhou Changhua¹,Wang Chunnian¹,Zhang Ning²,Cao Donglin³,Li Qing¹,Wang Zhong¹

Affiliation:

1. School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China;

2. Department of Urology, Peking University Cancer Hospital, Beijing Institute for Cancer Research, Beijing, China;

3. Department of Laboratory Medicine, Guangdong Second Provincial General Hospital, Guangzhou, China

Publisher

Informa UK Limited

Subject

Cancer Research,Oncology,Hematology

Link

https://www.tandfonline.com/doi/pdf/10.1080/10428194.2020.1728746

Reference42 articles.

1. Leukemia-Initiating Cells in T-Cell Acute Lymphoblastic Leukemia

2. Hematopoietic cell transplantation for acute lymphoblastic leukemia in adult patients

3. Molecular pathogenesis of T-cell leukaemia and lymphoma

4. The genetics and mechanisms of T cell acute lymphoblastic leukaemia

5. Genetic Basis of Acute Lymphoblastic Leukemia

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1. AKR1C3 in carcinomas: from multifaceted roles to therapeutic strategies;Frontiers in Pharmacology;2024-03-08

2. Structure-guided optimization of 3-hydroxybenzoisoxazole derivatives as inhibitors of Aldo-keto reductase 1C3 (AKR1C3) to target prostate cancer;European Journal of Medicinal Chemistry;2024-03

3. A novel AKR1C3 specific prodrug AST-3424 and its combination therapy in hepatocellular carcinoma;Journal of Pharmacological Sciences;2023-06

4. X-ray structure of human aldo–keto reductase 1C3 in complex with a bile acid fused tetrazole inhibitor: experimental validation, molecular docking and structural analysis;RSC Medicinal Chemistry;2023

5. AKR1C3 decreased CML sensitivity to Imatinib in bone marrow microenvironment via dysregulation of miR-379-5p;Cellular Signalling;2021-08

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