Pharmacologic inhibition of the ubiquitin-activating enzyme induces ER stress and apoptosis in chronic lymphocytic leukemia and ibrutinib-resistant mantle cell lymphoma cells-Reference-Cited by-同舟云学术

Pharmacologic inhibition of the ubiquitin-activating enzyme induces ER stress and apoptosis in chronic lymphocytic leukemia and ibrutinib-resistant mantle cell lymphoma cells

Published:2019-05-21 Issue:12 Volume:60 Page:2946-2950
ISSN:1042-8194
Container-title:Leukemia & Lymphoma
language:en
Short-container-title:Leukemia & Lymphoma

Author:

Best Scott¹,Liu Tingting¹,Bruss Nur¹,Kittai Adam¹,Berger Allison²,Danilov Alexey V.¹

Affiliation:

1. Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA;

2. Millennium Pharmaceuticals Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, Cambridge, MA, USA

Funder

Leukemia & Lymphoma Society Translational Research Program

Publisher

Informa UK Limited

Subject

Cancer Research,Oncology,Hematology

Link

https://www.tandfonline.com/doi/pdf/10.1080/10428194.2019.1616190

Reference10 articles.

1. Single-agent ibrutinib in treatment-naïve and relapsed/refractory chronic lymphocytic leukemia: a 5-year experience

2. Drugging the undruggables: exploring the ubiquitin system for drug development

3. A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment

4. B cell proliferation following CD40 stimulation results in the expression and activation of Src protein tyrosine kinase

5. The Nedd8-Activating Enzyme Inhibitor MLN4924 Thwarts Microenvironment-Driven NF-κB Activation and Induces Apoptosis in Chronic Lymphocytic Leukemia B Cells

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