Combinatorial Anticancer Drug Screen Identifies Off-Target Effects of Epigenetic Chemical Probes-Reference-Cited by-同舟云学术

Combinatorial Anticancer Drug Screen Identifies Off-Target Effects of Epigenetic Chemical Probes

Published:2022-09-09 Issue:10 Volume:17 Page:2801-2816
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Barghout Samir H.¹²³^ORCID,Mann Mandeep K.¹²^ORCID,Aman Ahmed⁴⁵^ORCID,Yu Yifan¹²,Alteen Matthew G.¹,Schimmer Aaron D.⁶⁷,Schapira Matthieu¹²^ORCID,Arrowsmith Cheryl H.¹⁶⁷^ORCID,Barsyte-Lovejoy Dalia¹²

Affiliation:

1. Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada

2. Department of Pharmacology & Toxicology, Faculty of Medicine, University of Toronto, Toronto, Ontario M5S 1A8, Canada

3. Department of Pharmacology & Toxicology, Faculty of Pharmacy, Tanta University, Tanta 31111, Egypt

4. Drug Discovery Program, Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada

5. Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario M5S 3M2, Canada

6. Department of Medical Biophysics, Faculty of Medicine, University of Toronto, Toronto, Ontario M5G 1L7, Canada

7. Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario M5G 1L7, Canada

Funder

Natural Sciences and Engineering Research Council of Canada

Mitacs

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.2c00451

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1. Cancer drug resistance: an evolving paradigm

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4. The Genetic/Non-genetic Duality of Drug ‘Resistance’ in Cancer

5. The cancer epigenome: Concepts, challenges, and therapeutic opportunities

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