Bridging inhaled aerosol dosimetry to physiologically based pharmacokinetic modeling for toxicological assessment: nicotine delivery systems and beyond
Author:
Affiliation:
1. PMI R&D, Philip Morris Products S.A, Neuchâtel, Switzerland;
2. Department of Applied Mathematics, Faculty EEMCS, University of Twente, Enschede, The Netherlands;
3. College of Public Health, University of South Florida, Tampa, FL, USA
Publisher
Informa UK Limited
Subject
Toxicology
Link
https://www.tandfonline.com/doi/pdf/10.1080/10408444.2019.1692780
Reference86 articles.
1. Association of Inhalation Toxicologists (AIT) Working Party Recommendation for Standard Delivered Dose Calculation and Expression in Non-Clinical Aerosol Inhalation Toxicology Studies with Pharmaceuticals
2. A Multiple-Path Model of Particle Deposition in the Rat Lung
3. Development of a realistic human respiratory tract cast representing physiological thermal conditions
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