Simulated pharmacokinetics of inhaled caffeine and melatonin from existing products indicate the lack of dosimetric considerations

Author:

Kolli Aditya R.ORCID,Kuczaj Arkadiusz K.,Calvino-Martin Florian,Hoeng Julia

Funder

Philip Morris International

Publisher

Elsevier BV

Reference39 articles.

1. Americans have turned to melatonin to soothe pandemic-induced stress;Akhtar,2021

2. Regional deposition of inhaled aerosol constituents from Electronic Nicotine Delivery Systems (ENDS) in the respiratory tract;Asgharian;J. Aerosol Sci.,2018

3. Simulation from ODE-based population PK/PD and systems pharmacology models in R with mrgsolve;Baron;Omega,2015

4. E-Cigarettes are being Marketed as “vitamin delivery” devices;Basáñez;Am. J. Publ. Health,2019

5. The absolute bioavailability of caffeine in man;Blanchard;Eur. J. Clin. Pharmacol.,1983

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