1. Institute of Clinical Medicine, Family Medicine, University of Turku and Turku University Hospital, Turku, Finland;
2. Central Satakunta Health Federation of Municipalities, Harjavalta, Finland;
3. Folkhälsan Research Center, Helsinki, Finland;
4. Unit of Primary Health Care, Kuopio University Hospital, Kuopio, Finland;
5. Department of Internal Medicine, University of Turku and Division of Medicine, Turku University Hospital, Turku, Finland;
6. Health Centre of Salo, Salo, Finland