Diethyldithiocarbamate encapsulation reduces toxicity and promotes leishmanicidal effect through apoptosis-like mechanism in promastigote and ROS production by macrophage

Author:

Assolini João Paulo1ORCID,Tomiotto-Pellissier Fernanda12ORCID,da Silva Bortoleti Bruna Taciane12ORCID,Gonçalves Manoela Daiele3ORCID,Sahd Claudia Stoeglehner1ORCID,Carloto Amanda Cristina Machado1ORCID,Feuser Paulo Emilio4ORCID,Cordeiro Arthur Poester4ORCID,Borghi Sergio Marques1ORCID,Verri Waldiceu Aparecido1ORCID,Sayer Claudia4ORCID,Hermes de Araújo Pedro Henrique4ORCID,Costa Idessania Nazareth1ORCID,Conchon-Costa Ivete1ORCID,Miranda-Sapla Milena Menegazzo1ORCID,Pavanelli Wander Rogério12ORCID

Affiliation:

1. Department of Pathological Sciences, Center of Biological Sciences, State University of Londrina, Londrina, PR, Brazil;

2. Biosciences and Biotechnology Postgraduate Program, Carlos Chagas Institute (ICC), Curitiba, PR, Brazil;

3. Department of Chemical, Center of Exact Sciences, State University of Londrina, Londrina, PR, Brazil;

4. Department of Chemical Engineering and Food Engineering, Federal University of Santa Catarina, Florianópolis, SC, Brazil

Publisher

Informa UK Limited

Subject

Pharmaceutical Science

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