Efficient Synthesis of the Nucleus of Atorvastatin Calcium

Author:

Xing Yuzhi,Chen Shipeng,Zhou Yingtao,Liu Na,Chen Ligong,Li Yang

Publisher

Informa UK Limited

Subject

Organic Chemistry

Reference12 articles.

1. Clinical Pharmacokinetics of Atorvastatin

2. Knoevenagel reactions with β-oxo acids. Regiospecific enol equivalents for syntheses of α,β-unsaturated ketones and of some β-ketols

3. Synthesis of deuterium-labeled atorvastatin and its metabolites for use as internal standards in a LC/MS/MS method developed for quantitation of the drug and its metabolites in human serum

4. (a) Lai, A. G.; Mehta, S. A.; Patel, H. K.; Bhagwat, S. WO Patent 2006110918 A1, 2006; (b) Sagyam, R. R.; Vurimidi, H.; Padi, P. R.; Ghanta, M. R.J. Heterocycl. Chem.2007,44, 923.

5. (a) Schoening, K.; Hartwig, J. WO Patent 03004457 A2, 2003; (b) Mathew, J.; Pathiaparampil, T. T.; Sridharan, M.; Sathya, S. P.; Ganesh, S. WO Patent 2004108660 A1, 2004; (c) Raju, S. J.; Sairam, P.; Sastry, R. S.; Rao, C. M.; Chiranjeevi, C.; Rao, G. M.; Trimurthulu, S.; Redddy, T. V.; Rao, T. V. WO Patent 2012143933 A1, 2012.

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