Alternative Approach to Synthesis of 3-(4-chloro butyl)-1H-indole-5-carbonitrile: A Key Intermediate of Vilazodone Hydrochloride, an Antidepressant Drug-Reference-Cited by-同舟云学术

Alternative Approach to Synthesis of 3-(4-chloro butyl)-1H-indole-5-carbonitrile: A Key Intermediate of Vilazodone Hydrochloride, an Antidepressant Drug

Published:2014-10-15 Issue:24 Volume:44 Page:3563-3571
ISSN:0039-7911
Container-title:Synthetic Communications
language:en
Short-container-title:Synthetic Communications

Author:

Anitha N.¹,Reddy B. Sudhakar¹,Sekhar N. M.¹,Reddy K. Venugopal²,Chandrasekhar E. R. R.¹

Affiliation:

1. a Product Delivery Team, Integrated Product Development , Dr. Reddy's Laboratories Ltd., Bachupalli , Qutubullapur , Andhra Pradesh , India

2. b Department of Chemistry , Osmania University , Hyderabad , Andhra Pradesh , India

Publisher

Informa UK Limited

Subject

Organic Chemistry

Link

https://www.tandfonline.com/doi/pdf/10.1080/00397911.2014.944268

Reference42 articles.

1. A Palladium-Catalyzed Strategy for the Preparation of Indoles: A Novel Entry into the Fischer Indole Synthesis

2. INDOLES FROM 2-METHYLNITROBENZENES BY CONDENSATION WITH FORMAMIDE ACETALS FOLLOWED BY REDUCTION: 4-BENZYLOXYINDOLE

3. The reaction of vinyl grignard reagents with 2-substituted nitroarenes: A new approach to the synthesis of 7-substituted indoles

4. Reactivity of nitro- and nitroso-arenes with vinyl grignard reagents: synthesis of 2-(trimethylsilyl)indoles

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3. Practical and Scalable Manufacturing Process for a Novel Dual-Acting Serotonergic Antidepressant Vilazodone;Organic Process Research & Development;2021-04-22

4. Novel Commercial Scale Synthetic Approach for 5-Cyanoindole: A Potential Intermediate for Vilazodone Hydrochloride, an Antidepressant Drug;Asian Journal of Chemistry;2020