Practical and Scalable Manufacturing Process for a Novel Dual-Acting Serotonergic Antidepressant Vilazodone
Author:
Affiliation:
1. Key Laboratory of Structure-Based Drug Design and Discovery, Shenyang Pharmaceutical University, Ministry of Education, Shenyang 110016, PR China
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.1c00069
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1. Vilazodone
2. A 1-Year, Open-Label Study Assessing the Safety and Tolerability of Vilazodone in Patients With Major Depressive Disorder
3. Vilazodone
4. Synthesis and Structure−Activity Relationship in a Class of Indolebutylpiperazines as Dual 5-HT1A Receptor Agonists and Serotonin Reuptake Inhibitors
5. Bathe, A. Method for the production of 5-(4-[4-(5-cyano-3-indolyl)-butyl]-1-piperazinyl)- benzofuran-2-carboxamide. WO 2006114202 A1, 2008.
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4. Development of a Robust and Scalable Process for the Large-Scale Preparation of Vilazodone;Organic Process Research & Development;2022-09-29
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