Understanding the relative affinity and specificity of the substrate binding site of protein kinase B for substrate-mimetic inhibitors-Reference-Cited by-同舟云学术

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Understanding the relative affinity and specificity of the substrate binding site of protein kinase B for substrate-mimetic inhibitors

Published:2017-05-02 Issue:17 Volume:43 Page:1459-1471
ISSN:0892-7022
Container-title:Molecular Simulation
language:en
Short-container-title:Molecular Simulation

Author:

Qian Haiyan¹,Chen Shifeng¹,Pan Youlu¹,Chen Jianzhong¹

Affiliation:

1. College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, P.R. China

Funder

This work was supported by National Natural Science Foundation of China

Publisher

Informa UK Limited

Subject

Condensed Matter Physics,General Materials Science,General Chemical Engineering,Modeling and Simulation,Information Systems,General Chemistry

Link

https://www.tandfonline.com/doi/pdf/10.1080/08927022.2017.1319062

Reference44 articles.

1. The Akt/PKB Family of Protein Kinases: A Review of Small Molecule Inhibitors and Progress Towards Target Validation

2. Recent Progress in the Development of ATP-Competitive and Allosteric Akt Kinase Inhibitors

3. Protein kinase B/Akt at a glance

4. Targeting Serine / Threonine Protein Kinase B / Akt and Cell-cycle Checkpoint Kinases for Treating Cancer

5. Advances of AKT Pathway in Human Oncogenesis and as a Target for Anti-Cancer Drug Discovery

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