Transitioning from Triton X-100 to Tergitol 15-S-9: impacts on diagnostic assays using viral PCR sample solution

Author:

Zorzoli Azul1ORCID,MacLean Alasdair2,Nicholson Scott2,Daniels Alison3ORCID,Hughes Stephen2,Bennet-Slater Susan2,Tait-Burkard Christine3ORCID,Sakka Noha El4,Gunson Rory2,Templeton Kate1ORCID

Affiliation:

1. Department of Clinical Microbiology, NHS Lothian, Edinburgh, UK

2. West of Scotland Specialist Virology Centre, Glasgow Royal Infirmary, Glasgow, UK

3. The Roslin Institute & Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, UK

4. Department of Medical Microbiology, NHS Grampian, Aberdeen, UK

Publisher

Informa UK Limited

Reference11 articles.

1. Analysis of Inactivation of SARS-CoV-2 by Specimen Transport Media, Nucleic Acid Extraction Reagents, Detergents, and Fixatives

2. European Agency for Safety and Health at Work. Regulation (EC) no 1907/2006. Safety and Health at Work EU-OSHA - REACH (Registration Evaluation Authorisation and Restriction of Chemicals). https://echa.europa.eu/substance-information/-/substanceinfo/100.123.919

3. Commission Regulation (EU) 2020/2160 of 18 December 2020 amending Annex XIV to regulation (EC) no 1907/2006 of the European Parliament and of the Council l as regards the substance group 4-(1,1,3,3-tetramethylbutyl)phenol, ethoxylated (covering well-defined substances and substances of unknown or variable composition, complex reaction products or biological materials, polymers and homologues);Commission Regulation of the European Union;Official J European Union.,2020

4. Identification of compendial nonionic detergents for the replacement of Triton X‐100 in bioprocessing

5. Identification and characterization of a Triton X‐100 replacement for virus inactivation

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