Analysis of Inactivation of SARS-CoV-2 by Specimen Transport Media, Nucleic Acid Extraction Reagents, Detergents, and Fixatives

Author:

Welch Stephen R.1,Davies Katherine A.1,Buczkowski Hubert1,Hettiarachchi Nipunadi1,Green Nicole1,Arnold Ulrike12,Jones Matthew1,Hannah Matthew J.1,Evans Reah1,Burton Christopher1,Burton Jane E.1,Guiver Malcolm3,Cane Patricia A.1,Woodford Neil4,Bruce Christine B.1,Roberts Allen D. G.1,Killip Marian J.1ORCID

Affiliation:

1. High Containment Microbiology, NIS Laboratories, National Infection Service, Public Health England, Colindale, London, United Kingdom

2. UK Public Health Rapid Support Team, Public Health England/London School of Hygiene and Tropical Medicine, London, United Kingdom

3. Virology Department, Clinical Sciences Laboratory, National Infection Service, Public Health England, Manchester Public Health Laboratory, Manchester, United Kingdom

4. NIS Laboratories, National Infection Service, Public Health England, Colindale, London, United Kingdom

Abstract

The COVID-19 pandemic has necessitated a multifaceted rapid response by the scientific community, bringing researchers, health officials, and industry together to address the ongoing public health emergency. To meet this challenge, participants need an informed approach for working safely with the etiological agent, the novel human coronavirus SARS-CoV-2. Work with infectious SARS-CoV-2 is currently restricted to high-containment laboratories, but material can be handled at a lower containment level after inactivation.

Funder

Public Health England

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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