Expedient Synthesis of Rupatadine

Author:

Agarwal Rajendra1,Bhirud Shekhar Bhaskar1,Bijukumar Gopinathenpillai1,Khude Gopal Dnyandev1

Affiliation:

1. a Chemical Process Research and Development , Research and Development Centre, Macleods Pharmaceuticals Ltd. , Mumbai, India

Publisher

Informa UK Limited

Subject

Organic Chemistry

Reference7 articles.

1. Carceller , E. Recasens , N. Almansa , C. Bartroli , J. Merlos , M. Giral , M. Rafanell , J. G. and Forn , J. Spanish Patent ES2042421. 1993.

2. “Unpublished results: HPLC analysis indicated 60.0% of monobromo compound”. The dibromo compound and the unreacted 3,5‐lutidine were in the range of ∼18–20%

3. Carceller , E. Recasens , N. Almansa , C. Bartroli , J. Merlos , M. Giral , M. Rafanell , J. G. and Forn , J. Spanish Patent ES2087818. 1996.

4. Carceller , E. Jiminez , P. J. and Salas , J. Spanish Patent ES2120899. 1998.

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