A novel miR1983-TLR7-IFNβ circuit licenses NK cells to kill glioma cells, and is under the control of galectin-1-Reference-Cited by-同舟云学术

A novel miR1983-TLR7-IFNβ circuit licenses NK cells to kill glioma cells, and is under the control of galectin-1

Published:2021-01-01 Issue:1 Volume:10 Page:
ISSN:2162-402X
Container-title:OncoImmunology
language:en
Short-container-title:OncoImmunology

Author:

Shah Diana¹²³⁴^ORCID,Comba Andrea¹²³⁴^ORCID,Faisal Syed M.¹²³⁴^ORCID,Kadiyala Padma¹²³⁴^ORCID,Baker Gregory J.¹²³⁴^ORCID,Alghamri Mahmoud S.¹²³⁴^ORCID,Doherty Robert¹²³⁴^ORCID,Zamler Daniel¹²³⁴^ORCID,Nuñez Gabriel⁵^ORCID,Castro Maria G.¹²³⁴^ORCID,Lowenstein Pedro R.¹²³⁴^ORCID

Affiliation:

1. Department of Neurosurgery, University of Michigan Medical School, Ann Arbor, MI, USA

2. Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, USA

3. Rogel Cancer Center, University of Michigan, Ann Arbor, MI USA

4. Cancer Biology Training Program, University of Michigan Medical School, Ann Arbor, MI, USA

5. Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA

Funder

National Institutes of Health

Publisher

Informa UK Limited

Subject

Oncology,Immunology,Immunology and Allergy

Link

https://www.tandfonline.com/doi/pdf/10.1080/2162402X.2021.1939601

Reference81 articles.

1. Apoptosis of T cells mediated by galectin-1

2. Targeted inhibition of galectin-1 gene expression in tumor cells results in heightened T cell-mediated rejection

3. Natural Killer Cells Eradicate Galectin-1–Deficient Glioma in the Absence of Adaptive Immunity

4. Natural killer cells require monocytic Gr-1+/CD11b+ myeloid cells to eradicate orthotopically engrafted glioma cells

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