Potential lung attack and lethality generated by EpCAM-specific CAR-T cells in immunocompetent mouse models-Reference-Cited by-同舟云学术

Potential lung attack and lethality generated by EpCAM-specific CAR-T cells in immunocompetent mouse models

Published:2020-01-01 Issue:1 Volume:9 Page:
ISSN:2162-402X
Container-title:OncoImmunology
language:en
Short-container-title:OncoImmunology

Author:

Qin Diyuan¹²,Li Dan³,Zhang Benxia¹,Chen Yue¹,Liao Xuelian⁴,Li Xiaoyu⁵,Alexander Peter B.⁶,Wang Yongsheng¹⁵,Li Qi-Jing²

Affiliation:

1. Department of Thoracic Oncology, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, China

2. Department of Immunology, Duke University Medical Center, Durham, NC, USA

3. Precision Medicine Center, Precision Medicine Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, China

4. Department of oncology, The First People’s Hospital of Jintang, Chengdu, China

5. Institute of Drug Clinical Trial, West China Hospital, Sichuan University, Chengdu, China

6. TCRCure Biopharma, Durham, NC, USA

Funder

National Nature Science Foundation of China

National Science and Technology Major Project

Sichuan Science and Technology Program

Publisher

Informa UK Limited

Subject

Oncology,Immunology,Immunology and Allergy

Link

https://www.tandfonline.com/doi/pdf/10.1080/2162402X.2020.1806009

Reference52 articles.

1. Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia

2. T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial

3. CD19-targeted CAR T-cell therapeutics for hematologic malignancies: interpreting clinical outcomes to date

4. CD19 CAR–T cells of defined CD4+:CD8+ composition in adult B cell ALL patients

5. Intent-to-treat leukemia remission by CD19 CAR T cells of defined formulation and dose in children and young adults

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