Human dihydrofolate reductase and thymidylate synthase form a complex in vitro and co-localize in normal and cancer cells
Author:
Affiliation:
1. Faculty of Chemistry, Warsaw University of Technology, Noakowskiego 3, 00-664 Warsaw, Poland
2. Nencki Institute of Experimental Biology, Polish Academy of Sciences, Pasteura 3, 02-093, Warsaw, Poland
Funder
Warsaw University of Technology
National Science Centre
Publisher
Informa UK Limited
Subject
Molecular Biology,General Medicine,Structural Biology
Link
https://www.tandfonline.com/doi/pdf/10.1080/07391102.2016.1186560
Reference72 articles.
1. Origins of the specificity of inhibitor P218 toward wild-type and mutantPfDHFR: a molecular dynamics analysis
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3. Small ubiquitin-like modifier-1 (SUMO-1) modification of thymidylate synthase and dihydrofolate reductase
4. Quartz crystal microbalance with dissipation and microscale thermophoresis as tools for investigation of protein complex formation between thymidylate synthesis cycle enzymes
5. Armstrong, R. D., Lewis, M., Stern, S. G. & Cadman, E. C. (1986). Acute effect of 5-fluorouracil on cytoplasmic and nuclear dihydrofolate reductase messenger RNA metabolism. Journal of Biological Chemistry, 261, 7366–7371. Retrieved from http://www.jbc.org/content/261/16/7366.abstract
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